Dopamine d2 Receptor anticorps (AA 9-21)

N° du produit ABIN289417

Cet anticorps Lapin Polyclonal détecte spécifiquement Dopamine d2 Receptor dans WB, IHC et ELISA. Il présente une réactivité envers Rat.

Aperçu rapide pour Dopamine d2 Receptor anticorps (AA 9-21) (ABIN289417)

Antigène: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Dopamine d2 Receptor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Dopamine d2 Receptor anticorps

Épitope: AA 9-21

Réactivité croisée (Details): This rat antigenic peptide is 100 % conserved in rat, pig, bovine, 92 % in mouse, and 78 % in human D1 (D1A/DRD1). No significant sequence homology exist with other dopamine receptors (D1B, D2-D5).

Purification: Affinity chromatography purified

Immunogène: Dopamine receptor 2 antibody was raised in rabbit using a 13 amino acid peptide of rat D1 R as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: ELISA: 0.5-1 µg/mL, IHC: 2-10 µg/mL, WB: 1-10 µg/mL
Optimal conditions should be determined by the investigator.

Commentaires:

Dopamine Receptor 2 Blocking peptide, (ABIN935313), is also available for use as a blocking control in assays to test for the specificity of this Dopamine Receptor 2 antibody.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized from PBS, with 0.1 % BSA, and 0.05 % NaN3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Détails sur Dopamine d2 Receptor

Antigène: Dopamine d2 Receptor (DRD2) (Dopamine Receptor D2 (DRD2))

Autre désignation: Dopamine Receptor 2

Sujet: Dopamine is an endogenous catecholamine that influences many cellular activities, including behavior, hormone synthesis and release, blood pressure and intracellular ion transport. A family of at least 5 Dopamine Receptors (DR) genes, D1-D5, have been identified based upon the amino acid identity, pharmacological specificity and effector responses. The D1 subtype is the most abundant dopamine receptor in the central nervous system. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events.

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Feeding Behaviour, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity